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How Lexapro Works

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Lexapro was developed by isolating the active component of Celexa® (citalopram HBr).

Lexapro is part of a family of drugs known as selective serotoninA neurotransmitter that is believed to influence mood. SSRIs help relieve the symptoms of depression by increasing the available supply of serotonin in the brain. reuptake inhibitors or SSRIs. Lexapro helps to increase the supply of a chemical messenger in the brain called serotonin. Lexapro appears to relieve the symptoms of depression and anxiety by increasing serotonin with minimal effect on many of the other chemicals in the brain.


How SSRIs Work

The brain chemistry of depression and anxiety is not fully understood. However, a growing body of evidence supports the view that people with these disorders have an imbalance of the brain's neurotransmitters. These are chemicals in the brain that allow nerve cells to communicate. One of these neurotransmitters is serotonin. An imbalance in serotonin may be an important factor in the development of depression and anxiety.

  • Serotonin is released from one nerve cell and becomes accessible to the next. In the process, some of the serotonin released is reabsorbed by the first nerve cell
  • SSRIs block the reabsorption of serotonin into the first nerve cell
  • It is this blocking action that causes an increased amount of serotonin to become available
  • This is how SSRIs affect the balance of serotonin in the brain
Important Risk Information