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TCAs (Tricyclic Antidepressants)
An older class of antidepressant drugs. Imipramine, amitriptyline, desipramine, and nortriptyline are examples of TCAs.


Titration
A stepwise increase or decrease in the prescribed dose of a given medicine.


Tolerability
The term used to indicate that the adverse events caused by a drug won't cause a patient to stop taking it. Clinical trials often measure the incidence of adverse events and the percentage of patients who stop therapy because of them.

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