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Causes of Generalized Anxiety Disorder

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Like other complex medical illnesses such as heart disease and diabetes, the exact causes of generalized anxiety disorder, or GAD, are difficult to explain. Research suggests that environmental and genetic factors (eg, a family history of GAD) may make a person more likely to develop the disorder.

Experts also agree that GAD may be caused by an imbalance of certain chemicals in the brain. In particular, 2 neurotransmitters (chemical message carriers) called dopamine and serotonin, are believed to regulate mood and behavior. Depression and/or other anxiety disorders are also common in people with GAD.

In people who develop GAD, anxiety symptoms often occur first during childhood or adolescence, but they can also begin in adulthood. GAD affects people of all ages, and the disorder is twice as likely to affect women as men. According to the National Institute of Mental Health, 4 million Americans suffer from GAD.1

Researchers continue to gain insights into the causes of anxiety disorders and their relationship to genetics and experience. Although the causes of GAD in a person are not always known, the symptoms are recognizable and effective treatments are available. For information regarding treatment with Lexapro see Lexapro as GAD treatment. If you feel you or someone you know may have GAD, review the symptoms of GAD and take a simple GAD Self-Test.

Reference: 1. Kessler RC, Chui W, Demler O, Walters E. Prevalence, Severity, and Comorbidity of 12-Month of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005; 62:617-627. 

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